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Proteostasis is adaptive: Balancing chaperone holdases against foldases
Because a cell must adapt to different stresses and growth rates, its proteostasis system must too. How do cells detect and adjust proteome folding to different conditions? Here, we explore a biophysical cost-benefit principle, namely that the cell should keep its proteome as folded as possible at t...
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| Publicado no: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7769611/ https://ncbi.nlm.nih.gov/pubmed/33315891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008460 |
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