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The R263K Dolutegravir Resistance-Associated Substitution Progressively Decreases HIV-1 Integration

Human immunodeficiency virus (HIV) infection persists despite decades of active antiretroviral therapy (ART), effectively preventing viral eradication. Treatment decreases plasma viral RNA, but viral DNA persists, mostly integrated within the genome of nucleated blood cells. Viral DNA blood levels c...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Mesplède, Thibault, Leng, Jing, Pham, Hanh Thi, Liang, Jiaming, Quan, Yudong, Han, Yingshan, Wainberg, Mark A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380839/
https://ncbi.nlm.nih.gov/pubmed/28377526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00157-17
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