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Modeling the Genetic Regulation of Cancer Metabolism: Interplay Between Glycolysis and Oxidative Phosphorylation

Abnormal metabolism is a hallmark of cancer, yet its regulation remains poorly understood. Cancer cells were considered to utilize primarily glycolysis for ATP production, referred to as the Warburg effect. However, recent evidence suggests that oxidative phosphorylation (OXPHOS) plays a crucial rol...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Yu, Linglin, Lu, Mingyang, Jia, Dongya, Ma, Jianpeng, Ben-Jacob, Eshel, Levine, Herbert, Kaipparettu, Benny Abraham, Onuchic, José N.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380541/
https://ncbi.nlm.nih.gov/pubmed/28202516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-2074
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