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Modeling the Genetic Regulation of Cancer Metabolism: Interplay Between Glycolysis and Oxidative Phosphorylation

Abnormal metabolism is a hallmark of cancer, yet its regulation remains poorly understood. Cancer cells were considered to utilize primarily glycolysis for ATP production, referred to as the Warburg effect. However, recent evidence suggests that oxidative phosphorylation (OXPHOS) plays a crucial rol...

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Bibliografische gegevens
Gepubliceerd in:Cancer Res
Hoofdauteurs: Yu, Linglin, Lu, Mingyang, Jia, Dongya, Ma, Jianpeng, Ben-Jacob, Eshel, Levine, Herbert, Kaipparettu, Benny Abraham, Onuchic, José N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380541/
https://ncbi.nlm.nih.gov/pubmed/28202516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-2074
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