Modeling the Genetic Regulation of Cancer Metabolism: Interplay Between Glycolysis and Oxidative Phosphorylation

Abnormal metabolism is a hallmark of cancer, yet its regulation remains poorly understood. Cancer cells were considered to utilize primarily glycolysis for ATP production, referred to as the Warburg effect. However, recent evidence suggests that oxidative phosphorylation (OXPHOS) plays a crucial rol...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Yu, Linglin, Lu, Mingyang, Jia, Dongya, Ma, Jianpeng, Ben-Jacob, Eshel, Levine, Herbert, Kaipparettu, Benny Abraham, Onuchic, José N.
Format: Artigo
Jezik:Inglês
Izdano: 2017
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380541/
https://ncbi.nlm.nih.gov/pubmed/28202516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-2074
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