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Modeling the Genetic Regulation of Cancer Metabolism: Interplay Between Glycolysis and Oxidative Phosphorylation

Abnormal metabolism is a hallmark of cancer, yet its regulation remains poorly understood. Cancer cells were considered to utilize primarily glycolysis for ATP production, referred to as the Warburg effect. However, recent evidence suggests that oxidative phosphorylation (OXPHOS) plays a crucial rol...

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Bibliographic Details
Published in:Cancer Res
Main Authors: Yu, Linglin, Lu, Mingyang, Jia, Dongya, Ma, Jianpeng, Ben-Jacob, Eshel, Levine, Herbert, Kaipparettu, Benny Abraham, Onuchic, José N.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380541/
https://ncbi.nlm.nih.gov/pubmed/28202516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-2074
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