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Quantifying Adhesion Mechanisms and Dynamics of Human Hematopoietic Stem and Progenitor Cells

Using planar lipid membranes with precisely defined concentrations of specific ligands, we have determined the binding strength between human hematopoietic stem cells (HSC) and the bone marrow niche. The relative significance of HSC adhesion to the surrogate niche models via SDF1α-CXCR4 or N-cadheri...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Burk, Alexandra S., Monzel, Cornelia, Yoshikawa, Hiroshi Y., Wuchter, Patrick, Saffrich, Rainer, Eckstein, Volker, Tanaka, Motomu, Ho, Anthony D.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380331/
https://ncbi.nlm.nih.gov/pubmed/25824493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09370
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