Quantifying Adhesion Mechanisms and Dynamics of Human Hematopoietic Stem and Progenitor Cells

Using planar lipid membranes with precisely defined concentrations of specific ligands, we have determined the binding strength between human hematopoietic stem cells (HSC) and the bone marrow niche. The relative significance of HSC adhesion to the surrogate niche models via SDF1α-CXCR4 or N-cadheri...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Burk, Alexandra S., Monzel, Cornelia, Yoshikawa, Hiroshi Y., Wuchter, Patrick, Saffrich, Rainer, Eckstein, Volker, Tanaka, Motomu, Ho, Anthony D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380331/
https://ncbi.nlm.nih.gov/pubmed/25824493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09370
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