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Simple Physical Model Unravels Influences of Chemokine on Shape Deformation and Migration of Human Hematopoietic Stem Cells

We studied the dynamic behavior of human hematopoietic stem cells (HSC) on the in vitro model of bone marrow surfaces in the absence and presence of chemokine (SDF1α). The deformation and migration of cells were investigated by varying the chemokine concentration and surface density of ligand molecu...

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Publicat a:Sci Rep
Autors principals: Ohta, Takao, Monzel, Cornelia, Becker, Alexandra S., Ho, Anthony D., Tanaka, Motomu
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045678/
https://ncbi.nlm.nih.gov/pubmed/30006633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28750-x
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