Evidence that Oxidative Dephosphorylation by the Non-heme Fe(II), α-Ketoglutarate:UMP Oxygenase Occurs by Stereospecific Hydroxylation

LipL and Cpr19 are non-heme, mononuclear Fe(II)-dependent, α-ketoglutarate (αKG):UMP oxygenases that catalyze the formation of CO(2), succinate, phosphate, and uridine-5′-aldehyde, the last of which is a biosynthetic precursor for several nucleoside antibiotics that inhibit bacterial translocase I (...

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Vydáno v:FEBS Lett
Hlavní autoři: Goswami, Anwesha, Liu, Xiaodong, Cai, Wenlong, Wyche, Thomas P, Bugni, Tim S, Meurillon, Maïa, Peyrottes, Suzanne, Perigaud, Christian, Nonaka, Koichi, Rohr, Jürgen, Van Lanen, Steven G
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380139/
https://ncbi.nlm.nih.gov/pubmed/28074470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12554
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