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Characterization of LipL as a Non-heme, Fe(II)-dependent α-Ketoglutarate:UMP Dioxygenase That Generates Uridine-5′-aldehyde during A-90289 Biosynthesis

Fe(II)- and α-ketoglutarate (α-KG)-dependent dioxygenases are a large and diverse superfamily of mononuclear, non-heme enzymes that perform a variety of oxidative transformations typically coupling oxidative decarboxylation of α-KG with hydroxylation of a prime substrate. The biosynthetic gene clust...

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Detalhes bibliográficos
Main Authors: Yang, Zhaoyong, Chi, Xiuling, Funabashi, Masanori, Baba, Satoshi, Nonaka, Koichi, Pahari, Pallab, Unrine, Jason, Jacobsen, Jesse M., Elliott, Gregory I., Rohr, Jürgen, Van Lanen, Steven G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048675/
https://ncbi.nlm.nih.gov/pubmed/21216959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.203562
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