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Biosynthetic Origin and Mechanism of Formation of the Aminoribosyl Moiety of Peptidyl Nucleoside Antibiotics

Several peptidyl nucleoside antibiotics that inhibit bacterial translocase I involved in peptidoglycan cell wall biosynthesis contain an aminoribosyl moiety, an unusual sugar appendage in natural products. We present here the delineation of the biosynthetic pathway for this moiety upon in vitro char...

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Detalhes bibliográficos
Main Authors: Chi, Xiuling, Pahari, Pallab, Nonaka, Koichi, Van Lanen, Steven G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174061/
https://ncbi.nlm.nih.gov/pubmed/21819104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja206304k
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