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The transcription factor Foxo1 controls germinal center B cell proliferation in response to T cell help
Germinal center (GC) B cells cycle between two states, the light zone (LZ) and the dark zone (DZ), and in the latter they proliferate and hypermutate their immunoglobulin genes. How this functional transition takes place is still controversial. In this study, we demonstrate that ablation of Foxo1 af...
Shranjeno v:
| izdano v: | J Exp Med |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5379976/ https://ncbi.nlm.nih.gov/pubmed/28351982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161263 |
| Oznake: |
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