Inactivation of ID4 promotes a CRPC phenotype with constitutive AR activation through FKBP52

Castration‐resistant prostate cancer (CRPC) is the emergence of prostate cancer cells that have adapted to the androgen‐depleted environment of the prostate. In recent years, targeting multiple chaperones and co‐chaperones (e.g., Hsp27, FKBP52) that promote androgen receptor (AR) signaling and/or no...

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Udgivet i:Mol Oncol
Main Authors: Joshi, Jugal Bharat, Patel, Divya, Morton, Derrick J., Sharma, Pankaj, Zou, Jin, Hewa Bostanthirige, Dhanushka, Gorantla, Yamini, Nagappan, Peri, Komaragiri, Shravan Kumar, Sivils, Jeffrey C., Xie, Huan, Palaniappan, Ravi, Wang, Guangdi, Cox, Marc B., Chaudhary, Jaideep
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378613/
https://ncbi.nlm.nih.gov/pubmed/28252832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12028
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