Inactivation of ID4 promotes a CRPC phenotype with constitutive AR activation through FKBP52

Castration‐resistant prostate cancer (CRPC) is the emergence of prostate cancer cells that have adapted to the androgen‐depleted environment of the prostate. In recent years, targeting multiple chaperones and co‐chaperones (e.g., Hsp27, FKBP52) that promote androgen receptor (AR) signaling and/or no...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Joshi, Jugal Bharat, Patel, Divya, Morton, Derrick J., Sharma, Pankaj, Zou, Jin, Hewa Bostanthirige, Dhanushka, Gorantla, Yamini, Nagappan, Peri, Komaragiri, Shravan Kumar, Sivils, Jeffrey C., Xie, Huan, Palaniappan, Ravi, Wang, Guangdi, Cox, Marc B., Chaudhary, Jaideep
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378613/
https://ncbi.nlm.nih.gov/pubmed/28252832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12028
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