Inactivation of ID4 promotes a CRPC phenotype with constitutive AR activation through FKBP52

Castration‐resistant prostate cancer (CRPC) is the emergence of prostate cancer cells that have adapted to the androgen‐depleted environment of the prostate. In recent years, targeting multiple chaperones and co‐chaperones (e.g., Hsp27, FKBP52) that promote androgen receptor (AR) signaling and/or no...

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Dades bibliogràfiques
Publicat a:Mol Oncol
Autors principals: Joshi, Jugal Bharat, Patel, Divya, Morton, Derrick J., Sharma, Pankaj, Zou, Jin, Hewa Bostanthirige, Dhanushka, Gorantla, Yamini, Nagappan, Peri, Komaragiri, Shravan Kumar, Sivils, Jeffrey C., Xie, Huan, Palaniappan, Ravi, Wang, Guangdi, Cox, Marc B., Chaudhary, Jaideep
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378613/
https://ncbi.nlm.nih.gov/pubmed/28252832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12028
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