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Memory and synaptic plasticity are impaired by dysregulated hippocampal O-GlcNAcylation

O-GlcNAcylated proteins are abundant in the brain and are associated with neuronal functions and neurodegenerative diseases. Although several studies have reported the effects of aberrant regulation of O-GlcNAcylation on brain function, the roles of O-GlcNAcylation in synaptic function remain unclea...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yang, Yong Ryoul, Song, Seungju, Hwang, Hongik, Jung, Jung Hoon, Kim, Su-Jeong, Yoon, Sora, Hur, Jin-Hoe, Park, Jae-Il, Lee, Cheol, Nam, Dougu, Seo, Young-Kyo, Kim, Joung-Hun, Rhim, Hyewhon, Suh, Pann-Ghill
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377249/
https://ncbi.nlm.nih.gov/pubmed/28368052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44921
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