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Elevated O-GlcNAcylation induces an antidepressant-like phenotype and decreased inhibitory transmission in medial prefrontal cortex

Depression is a devastating mental disorder affected by multiple factors that can have genetic, environmental, or metabolic causes. Although previous studies have reported an association of dysregulated glucose metabolism with depression, its underlying mechanism remains elusive at the molecular lev...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Cho, Yoonjeong, Hwang, Hongik, Rahman, Md. Ataur, Chung, ChiHye, Rhim, Hyewhon
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181662/
https://ncbi.nlm.nih.gov/pubmed/32332789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63819-6
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