Pharmacological Inhibition of O-GlcNAc Transferase Promotes mTOR-Dependent Autophagy in Rat Cortical Neurons

O-GlcNAc transferase (OGT) is a ubiquitous enzyme that regulates the addition of β-N-acetylglucosamine (O-GlcNAc) to serine and threonine residues of target proteins. Autophagy is a cellular process of self-digestion, in which cytoplasmic resources, such as aggregate proteins, toxic compounds, damag...

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Detaylı Bibliyografya
Yayımlandı:Brain Sci
Asıl Yazarlar: Rahman, Md. Ataur, Cho, Yoonjeong, Hwang, Hongik, Rhim, Hyewhon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Communication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763293/
https://ncbi.nlm.nih.gov/pubmed/33317171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/brainsci10120958
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