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Memory and synaptic plasticity are impaired by dysregulated hippocampal O-GlcNAcylation

O-GlcNAcylated proteins are abundant in the brain and are associated with neuronal functions and neurodegenerative diseases. Although several studies have reported the effects of aberrant regulation of O-GlcNAcylation on brain function, the roles of O-GlcNAcylation in synaptic function remain unclea...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Yang, Yong Ryoul, Song, Seungju, Hwang, Hongik, Jung, Jung Hoon, Kim, Su-Jeong, Yoon, Sora, Hur, Jin-Hoe, Park, Jae-Il, Lee, Cheol, Nam, Dougu, Seo, Young-Kyo, Kim, Joung-Hun, Rhim, Hyewhon, Suh, Pann-Ghill
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377249/
https://ncbi.nlm.nih.gov/pubmed/28368052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44921
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