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Supraphysiological levels of GDF11 induce striated muscle atrophy

Growth and differentiation factor (GDF) 11 is a member of the transforming growth factor β superfamily recently identified as a potential therapeutic for age‐related cardiac and skeletal muscle decrements, despite high homology to myostatin (Mstn), a potent negative regulator of muscle mass. Though...

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Detalles Bibliográficos
Publicado en:EMBO Mol Med
Main Authors: Hammers, David W, Merscham‐Banda, Melissa, Hsiao, Jennifer Ying, Engst, Stefan, Hartman, James J, Sweeney, H Lee
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376753/
https://ncbi.nlm.nih.gov/pubmed/28270449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201607231
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