Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle

Parabiosis experiments indicate that impaired regeneration in aged mice is reversible by exposure to a young circulation, suggesting that young blood contains humoral “rejuvenating” factors that can restore regenerative function. Here, we demonstrate that the circulating protein Growth Differentiati...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sinha, Manisha, Jang, Young C., Oh, Juhyun, Khong, Danika, Wu, Elizabeth Y., Manohar, Rohan, Miller, Christine, Regalado, Samuel G., Loffredo, Francesco S., Pancoast, James R., Hirshman, Michael F., Lebowitz, Jessica, Shadrach, Jennifer L., Cerletti, Massimiliano, Kim, Mi-Jeong, Serwold, Thomas, Goodyear, Laurie J., Rosner, Bernard, Lee, Richard T., Wagers, Amy J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104429/
https://ncbi.nlm.nih.gov/pubmed/24797481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1251152
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados