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Short-term calorie restriction enhances skeletal muscle stem cell function

Calorie restriction (CR) extends lifespan and ameliorates age-related pathologies in most species studied; yet the mechanisms underlying these effects remain unclear. Using mouse skeletal muscle as a model, we show that CR acts in part by enhancing the function of tissue-specific stem cells. Even sh...

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Detalhes bibliográficos
Main Authors: Cerletti, Massimiliano, Jang, Young C., Finley, Lydia W.S., Haigis, Marcia C., Wagers, Amy J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561899/
https://ncbi.nlm.nih.gov/pubmed/22560075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.04.002
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