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Transfer of disrupted-in-schizophrenia 1 aggregates between neuronal-like cells occurs in tunnelling nanotubes and is promoted by dopamine

The disrupted-in-schizophrenia 1 (DISC1) gene was identified as a genetic risk factor for chronic mental illnesses (CMI) such as schizophrenia, bipolar disorder and severe recurrent depression. Insoluble aggregated DISC1 variants were found in the cingular cortex of sporadic, i.e. non-genetic, CMI p...

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Vydáno v:Open Biol
Hlavní autoři: Zhu, Seng, Abounit, Saïda, Korth, Carsten, Zurzolo, Chiara
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376705/
https://ncbi.nlm.nih.gov/pubmed/28275106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160328
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