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Tunneling nanotubes spread fibrillar α‐synuclein by intercellular trafficking of lysosomes

Synucleinopathies such as Parkinson's disease are characterized by the pathological deposition of misfolded α‐synuclein aggregates into inclusions throughout the central and peripheral nervous system. Mounting evidence suggests that intercellular propagation of α‐synuclein aggregates may contri...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Abounit, Saïda, Bousset, Luc, Loria, Frida, Zhu, Seng, de Chaumont, Fabrice, Pieri, Laura, Olivo‐Marin, Jean‐Christophe, Melki, Ronald, Zurzolo, Chiara
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048354/
https://ncbi.nlm.nih.gov/pubmed/27550960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593411
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