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PTENβ is an alternatively translated isoform of PTEN that regulates rDNA transcription

PTEN is a critical tumour suppressor that is frequently mutated in human cancer. We have previously identified a CUG initiated PTEN isoform designated PTENα, which functions in mitochondrial bioenergetics. Here we report the identification of another N-terminal extended PTEN isoform, designated PTEN...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liang, Hui, Chen, Xi, Yin, Qi, Ruan, Danhui, Zhao, Xuyang, Zhang, Cong, McNutt, Michael A., Yin, Yuxin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376652/
https://ncbi.nlm.nih.gov/pubmed/28332494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14771
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