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Nucleolar retention of a translational C/EBPα isoform stimulates rDNA transcription and cell size

The messenger RNA of the intronless CEBPA gene is translated into distinct protein isoforms through the usage of consecutive translation initiation sites. These translational isoforms have distinct functions in the regulation of differentiation and proliferation due to the presence of different N-te...

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Détails bibliographiques
Auteurs principaux: Müller, Christine, Bremer, Anna, Schreiber, Sandra, Eichwald, Sabrina, Calkhoven, Cornelis F
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810377/
https://ncbi.nlm.nih.gov/pubmed/20075868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.404
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