A Combined NMR and SAXS Analysis of the Partially Folded Cataract-Associated V75D γD-Crystallin

A cataract is a pathological condition characterized by the clouding of the normally clear eye lens brought about by deposition of crystallin proteins in the lens fiber cells. These protein aggregates reduce visual acuity by scattering or blocking incoming light. Chemical damage to proteins of the c...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Whitley, Matthew J., Xi, Zhaoyong, Bartko, Jonathan C., Jensen, Malene Ringkjøbing, Blackledge, Martin, Gronenborn, Angela M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2017
Schlagworte:
Proteins
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376099/
https://ncbi.nlm.nih.gov/pubmed/28355541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.02.010
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