A Combined NMR and SAXS Analysis of the Partially Folded Cataract-Associated V75D γD-Crystallin

A cataract is a pathological condition characterized by the clouding of the normally clear eye lens brought about by deposition of crystallin proteins in the lens fiber cells. These protein aggregates reduce visual acuity by scattering or blocking incoming light. Chemical damage to proteins of the c...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Whitley, Matthew J., Xi, Zhaoyong, Bartko, Jonathan C., Jensen, Malene Ringkjøbing, Blackledge, Martin, Gronenborn, Angela M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Proteins
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376099/
https://ncbi.nlm.nih.gov/pubmed/28355541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.02.010
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