Assessing the Structures and Interactions of γD-Crystallin Deamidation Variants

Cataracts involve the deposition of the crystallin proteins in the vertebrate eye lens, causing opacification and blindness. They are associated with either genetic mutation or protein damage that accumulates over the lifetime of the organism. Deamidation of Asn residues in several different crystal...

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Foilsithe in:Structure
Main Authors: Guseman, Alex J., Whitley, Matthew J., González, Jeremy J., Rathi, Nityam, Ambarian, Mikayla, Gronenborn, Angela M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935750/
https://ncbi.nlm.nih.gov/pubmed/33264606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2020.11.006
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