Investigation and identification of protein carbonylation sites based on position-specific amino acid composition and physicochemical features

BACKGROUND: Protein carbonylation, an irreversible and non-enzymatic post-translational modification (PTM), is often used as a marker of oxidative stress. When reactive oxygen species (ROS) oxidized the amino acid side chains, carbonyl (CO) groups are produced especially on Lysine (K), Arginine (R),...

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Vydáno v:BMC Bioinformatics
Hlavní autoři: Weng, Shun-Long, Huang, Kai-Yao, Kaunang, Fergie Joanda, Huang, Chien-Hsun, Kao, Hui-Ju, Chang, Tzu-Hao, Wang, Hsin-Yao, Lu, Jang-Jih, Lee, Tzong-Yi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374553/
https://ncbi.nlm.nih.gov/pubmed/28361707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1472-8
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