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MDD-carb: a combinatorial model for the identification of protein carbonylation sites with substrate motifs

BACKGROUND: Carbonylation, which takes place through oxidation of reactive oxygen species (ROS) on specific residues, is an irreversibly oxidative modification of proteins. It has been reported that the carbonylation is related to a number of metabolic or aging diseases including diabetes, chronic l...

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Bibliografske podrobnosti
izdano v:BMC Syst Biol
Main Authors: Kao, Hui-Ju, Weng, Shun-Long, Huang, Kai-Yao, Kaunang, Fergie Joanda, Hsu, Justin Bo-Kai, Huang, Chien-Hsun, Lee, Tzong-Yi
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5763492/
https://ncbi.nlm.nih.gov/pubmed/29322938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-017-0511-4
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