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Rational mutagenesis by engineering disulphide bonds improves Kluyveromyces lactis beta-galactosidase for high-temperature industrial applications

Kluyveromyces lactis β-galactosidase (Kl-β-Gal) is one of the most important enzymes in the dairy industry. The poor stability of this enzyme limits its use in the synthesis of galactooligosaccharides (GOS) and other applications requiring high operational temperature. To obtain thermoresistant vari...

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發表在:Sci Rep
Main Authors: Rico-Díaz, Agustín, Álvarez-Cao, María-Efigenia, Escuder-Rodríguez, Juan-José, González-Siso, María-Isabel, Cerdán, M. Esperanza, Becerra, Manuel
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374532/
https://ncbi.nlm.nih.gov/pubmed/28361909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45535
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