The antimicrobial effects of the alginate oligomer OligoG CF-5/20 are independent of direct bacterial cell membrane disruption

Concerns about acquisition of antibiotic resistance have led to increasing demand for new antimicrobial therapies. OligoG CF-5/20 is an alginate oligosaccharide previously shown to have antimicrobial and antibiotic potentiating activity. We investigated the structural modification of the bacterial c...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Pritchard, Manon F., Powell, Lydia C., Khan, Saira, Griffiths, Peter C., Mansour, Omar T., Schweins, Ralf, Beck, Konrad, Buurma, Niklaas J., Dempsey, Christopher E., Wright, Chris J., Rye, Philip D., Hill, Katja E., Thomas, David W., Ferguson, Elaine L.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374485/
https://ncbi.nlm.nih.gov/pubmed/28361894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44731
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