Phenotypic and Genotypic Adaptations in Pseudomonas aeruginosa Biofilms following Long-Term Exposure to an Alginate Oligomer Therapy

Chronic Pseudomonas aeruginosa lung infections in cystic fibrosis (CF) evolve to generate environmentally adapted biofilm communities, leading to increased patient morbidity and mortality. OligoG CF-5/20, a low-molecular-weight inhaled alginate oligomer therapy, is currently in phase IIb/III clinica...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:mSphere
Hauptverfasser: Oakley, Juliette L., Weiser, Rebecca, Powell, Lydia C., Forton, Julian, Mahenthiralingam, Eshwar, Rye, Philip D., Hill, Katja E., Thomas, David W., Pritchard, Manon F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7845618/
https://ncbi.nlm.nih.gov/pubmed/33472983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.01216-20
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge