The antimicrobial effects of the alginate oligomer OligoG CF-5/20 are independent of direct bacterial cell membrane disruption

Concerns about acquisition of antibiotic resistance have led to increasing demand for new antimicrobial therapies. OligoG CF-5/20 is an alginate oligosaccharide previously shown to have antimicrobial and antibiotic potentiating activity. We investigated the structural modification of the bacterial c...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pritchard, Manon F., Powell, Lydia C., Khan, Saira, Griffiths, Peter C., Mansour, Omar T., Schweins, Ralf, Beck, Konrad, Buurma, Niklaas J., Dempsey, Christopher E., Wright, Chris J., Rye, Philip D., Hill, Katja E., Thomas, David W., Ferguson, Elaine L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374485/
https://ncbi.nlm.nih.gov/pubmed/28361894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44731
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