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Smad4 regulates growth plate matrix production and chondrocyte polarity

Smad4 is an intracellular effector of the TGFβ family that has been implicated in Myhre syndrome, a skeletal dysplasia characterized by short stature, brachydactyly and stiff joints. The TGFβ pathway also plays a critical role in the development, organization and proliferation of the growth plate, a...

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Podrobná bibliografie
Vydáno v:Biol Open
Hlavní autoři: Whitaker, Amanda T., Berthet, Ellora, Cantu, Andrea, Laird, Diana J., Alliston, Tamara
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374397/
https://ncbi.nlm.nih.gov/pubmed/28167493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.021436
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