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Smad4 regulates growth plate matrix production and chondrocyte polarity
Smad4 is an intracellular effector of the TGFβ family that has been implicated in Myhre syndrome, a skeletal dysplasia characterized by short stature, brachydactyly and stiff joints. The TGFβ pathway also plays a critical role in the development, organization and proliferation of the growth plate, a...
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Publicado no: | Biol Open |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Company of Biologists Ltd
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5374397/ https://ncbi.nlm.nih.gov/pubmed/28167493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.021436 |
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