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Smad7 regulates terminal maturation of chondrocytes in the growth plate

Members of the bone morphogenetic protein (BMP) superfamily, including transforming growth factor-betas (TGFβ), regulate multiple aspects of chondrogenesis. Smad7 is an intracellular inhibitor of BMP and TGFβ signaling. Studies in which Smad7 was overexpressed in chondrocytes demonstrated that Smad7...

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Dades bibliogràfiques
Publicat a:Dev Biol
Autors principals: Estrada, Kristine D., Wang, Weiguang, Retting, Kelsey N., Chien, Chengan T., Elkhoury, Fuad F., Heuchel, Rainer, Lyons, Karen M.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267888/
https://ncbi.nlm.nih.gov/pubmed/23994637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.08.021
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