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BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation

Bone morphogenetic protein (BMP) signaling is required for endochondral bone formation. However, whether or not the effects of BMPs are mediated via canonical Smad pathways or through noncanonical pathways is unknown. In this study we have determined the role of receptor Smads 1, 5 and 8 in chondrog...

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Autors principals: Retting, Kelsey N., Song, Buer, Yoon, Byeong S., Lyons, Karen M.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668702/
https://ncbi.nlm.nih.gov/pubmed/19224984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.029926
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