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Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate

TGFβs act through canonical and non-canonical pathways, and canonical signals are transduced via Smad2 and Smad3. However, the contribution of canonical vs. non-canonical pathways in cartilage is unknown because the role of Smad2 in chondrogenesis has not been investigated in vivo. Therefore, we ana...

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書目詳細資料
發表在:PLoS Genet
Main Authors: Wang, Weiguang, Song, Buer, Anbarchian, Teni, Shirazyan, Anna, Sadik, Joshua E., Lyons, Karen M.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065210/
https://ncbi.nlm.nih.gov/pubmed/27741240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006352
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