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Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate
TGFβs act through canonical and non-canonical pathways, and canonical signals are transduced via Smad2 and Smad3. However, the contribution of canonical vs. non-canonical pathways in cartilage is unknown because the role of Smad2 in chondrogenesis has not been investigated in vivo. Therefore, we ana...
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| Pubblicato in: | PLoS Genet |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5065210/ https://ncbi.nlm.nih.gov/pubmed/27741240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006352 |
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