Diabetic polyneuropathy, sensory neurons, nuclear structure and spliceosome alterations: a role for CWC22

Unique deficits in the function of adult sensory neurons as part of their early neurodegeneration might account for progressive polyneuropathy during chronic diabetes mellitus. Here, we provide structural and functional evidence for aberrant pre-mRNA splicing in a chronic type 1 model of experimenta...

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Bibliografske podrobnosti
izdano v:Dis Model Mech
Main Authors: Kobayashi, Masaki, Chandrasekhar, Ambika, Cheng, Chu, Martinez, Jose A., Ng, Hilarie, de la Hoz, Cristiane, Zochodne, Douglas W.
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374325/
https://ncbi.nlm.nih.gov/pubmed/28250049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.028225
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