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Diabetic polyneuropathy, sensory neurons, nuclear structure and spliceosome alterations: a role for CWC22

Unique deficits in the function of adult sensory neurons as part of their early neurodegeneration might account for progressive polyneuropathy during chronic diabetes mellitus. Here, we provide structural and functional evidence for aberrant pre-mRNA splicing in a chronic type 1 model of experimenta...

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Dades bibliogràfiques
Publicat a:Dis Model Mech
Autors principals: Kobayashi, Masaki, Chandrasekhar, Ambika, Cheng, Chu, Martinez, Jose A., Ng, Hilarie, de la Hoz, Cristiane, Zochodne, Douglas W.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374325/
https://ncbi.nlm.nih.gov/pubmed/28250049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.028225
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