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Differential roles of two delayed rectifier potassium currents in regulation of ventricular action potential duration and arrhythmia susceptibility

KEY POINTS: Arrhythmias result from disruptions to cardiac electrical activity, although the factors that control cellular action potentials are incompletely understood. We combined mathematical modelling with experiments in heart cells from guinea pigs to determine how cellular electrical activity...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Devenyi, Ryan A., Ortega, Francis A., Groenendaal, Willemijn, Krogh‐Madsen, Trine, Christini, David J., Sobie, Eric A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374112/
https://ncbi.nlm.nih.gov/pubmed/27779762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273191
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