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Voltage and Calcium Dynamics Both Underlie Cellular Alternans in Cardiac Myocytes

Cardiac alternans, a putative trigger event for cardiac reentry, is a beat-to-beat alternation in membrane potential and calcium transient. Alternans was originally attributed to instabilities in transmembrane ion channel dynamics (i.e., the voltage mechanism). As of this writing, the predominant vi...

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Detalhes bibliográficos
Main Authors: Groenendaal, Willemijn, Ortega, Francis A., Krogh-Madsen, Trine, Christini, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052344/
https://ncbi.nlm.nih.gov/pubmed/24853751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.03.048
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