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Voltage and Calcium Dynamics Both Underlie Cellular Alternans in Cardiac Myocytes

Cardiac alternans, a putative trigger event for cardiac reentry, is a beat-to-beat alternation in membrane potential and calcium transient. Alternans was originally attributed to instabilities in transmembrane ion channel dynamics (i.e., the voltage mechanism). As of this writing, the predominant vi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Groenendaal, Willemijn, Ortega, Francis A., Krogh-Madsen, Trine, Christini, David J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052344/
https://ncbi.nlm.nih.gov/pubmed/24853751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.03.048
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