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Inferring the Cellular Origin of Voltage and Calcium Alternans from the Spatial Scales of Phase Reversal during Discordant Alternans

Beat-to-beat alternation of the action potential duration (APD) in paced cardiac cells has been linked to the onset of lethal arrhythmias. Both experimental and theoretical studies have shown that alternans at the single cell level can be caused by unstable membrane voltage (V(m)) dynamics linked to...

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Autors principals: Sato, Daisuke, Shiferaw, Yohannes, Qu, Zhilin, Garfinkel, Alan, Weiss, James N., Karma, Alain
Format: Artigo
Idioma:Inglês
Publicat: Biophysical Society 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783870/
https://ncbi.nlm.nih.gov/pubmed/17172300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.100982
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