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Formation of Spatially Discordant Alternans Due to Fluctuations and Diffusion of Calcium

Spatially discordant alternans (SDA) of action potential duration (APD) is a phenomenon where different regions of cardiac tissue exhibit an alternating sequence of APD that are out-of-phase. SDA is arrhythmogenic since it can induce spatial heterogeneity of refractoriness, which can cause wavebreak...

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Главные авторы: Sato, Daisuke, Bers, Donald M., Shiferaw, Yohannes
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877395/
https://ncbi.nlm.nih.gov/pubmed/24392005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085365
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