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Stretch-Activated Current Can Promote or Suppress Cardiac Alternans Depending on Voltage-Calcium Interaction

Cardiac alternans has been linked to the onset of ventricular fibrillation and ventricular tachycardia, leading to life-threatening arrhythmias. Here, we investigated the effects of stretch-activated currents (I(SAC)) on alternans using a physiologically detailed model of the ventricular myocyte. We...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biophys J
Main Authors: Galice, Samuel, Bers, Donald M., Sato, Daisuke
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919541/
https://ncbi.nlm.nih.gov/pubmed/27332125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.05.026
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